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Prebiotics reduce body fat in overweight children

"This is a well-designed trial that demonstrates how a prebiotic could potentially help combat one of the most prevalent and costly conditions afflicting children in the developed world -- overnutrition -- by targeting the gut microbiome ," said Geoffrey A. Preidis, MD, PhD, a member of the AGA Center for Gut Microbiome Research and Education scientific advisory board. "It is promising to see this evidence that alteration of the gut microbiota can be used to restore health. As a clinician, I hope that continued research into prebiotics will lead to a new strategy for the treatment of obesity." For this study, researchers from the University of Calgary, Alberta, Canada, performed a double-blind, placebo-controlled trial with 42 participants . Participants included children, 7 to 12 years old, who were classified as overweight or obese (>85th percentile of body mass index) but otherwise healthy. Participants were randomly assigned to groups given either the pre